Are you an experienced and proactive Clinical Data Manager with a strong background in oncology and real-world evidence (RWE)? Do you have the clinical expertise to contribute to scientific discussions, support internal training, and help develop study proposals? If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Clinical Operations Team as a Clinical Data Manager of Oncology &amp; Real-World Evidence (RWE), and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.  This is a hybrid opportunity, requiring 3 days onsite our corporate office in either Rolle, CH or Bidart, FR.   Our Mission   We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.    Your Mission   As our Clinical Data Manager of Oncology &amp; RWE, you will lead the data management activities across clinical studies and contribute clinical insight to enhance the quality and relevance of medical content and study outputs. You will interface closely with our BioPharma partners in the context of collaborative efforts. You will work closely with clinical operations, medical affairs, and data science teams to ensure high-quality data collection, interpretation, and communication.  The value you bring <ul><li>Lead end-to-end data management activities for observational and real-world studies in oncology </li></ul><ul><li>Define and maintain data management plans, data dictionaries, and quality control processes </li></ul><ul><li>Oversee data collection, validation, and cleaning in collaboration with clinical and technical teams </li></ul><ul><li>Apply clinical oncology knowledge to ensure meaningful data capture and interpretation </li></ul><ul><li>Review and annotate CRFs, ensure consistency of clinical data with study objectives and endpoints </li></ul><ul><li>Contribute to the development of medical and scientific content for internal trainings, study proposals, and publications </li></ul><ul><li>Support discussions with clinical experts and oncologists by providing data-driven insights and context </li></ul><ul><li>Interface with BioPharma partners in the context of collaborative efforts </li></ul><ul><li>Collaborate cross-functionally with biostatistics, medical, regulatory, and business development teams </li></ul><ul><li>Ensure data compliance with relevant standards (e.g., GPP, GDPR, FAIR principles, etc.) </li></ul><ul><li>Degree in Life Sciences, Pharmacy, biology, or equivalent (Master’s or higher preferred) </li></ul><ul><li>Minimum 5 years of experience in data management for clinical or real-world studies </li></ul><ul><li>Strong clinical background in oncology — ability to interpret clinical context from raw data </li></ul><ul><li>Solid understanding of RWE study design, endpoints, and data sources </li></ul><ul><li>Experience working in cross-functional, matrixes environments </li></ul><ul><li>Strong communication skills; able to translate complex data into clear messages for internal and external stakeholders </li></ul><ul><li>Fluent in English (written and spoken); French is a plus </li></ul><ul><li>Familiarity with CDISC standards, EDC systems, and relevant data privacy regulations is an asset </li></ul>As an international organization, English is our primary business language and as part of your recruitment journey, you should expect to meet English-only speakers. For best chances of success, you should include your CV in English. Unfortunately, non-English CVs have a high likelihood of being rejected at application stage.