This is an exciting opportunity for a clinical biostatistician to play a key role in the design and analysis of oncology studies within Natera’s ctDNA diagnostic portfolio. As a Lead Biostatistician, you will drive the design, analysis, and reporting across multiple oncology clinical trials. The ideal candidate brings a strong applied statistics background, a proactive mindset, and excellent collaboration skills.  PRIMARY RESPONSIBILITIES: <ul> <li> Study Design &amp; Analysis: Provide technical leadership in the design, execution, and analysis of oncology clinical utility studies, including endpoint selection, sample size estimation, and methods strategy. Execute statistical analyses according to plans and protocols, as well as exploratory or ad-hoc investigations. </li> <li> Cross-Functional Collaboration: Act as the statistical representative on project teams. Partner with clinical, translational, and medical teams to align study designs with clinical research objectives. Effectively convey statistical concepts and results to collaborators and stakeholders. </li> <li> Documentation &amp; Reporting: Contribute to protocols, statistical analysis plans (SAPs), tables/figures/listings (TFLs), and study reports. Ensure documentation meets internal standards and regulatory expectations. </li> <li> Innovation &amp; Improvement: Apply emerging or advanced statistical methods where appropriate. Contribute to the improvement of internal tools, templates, and statistical best practices. </li> </ul> QUALIFICATIONS: <ul> <li> Ph.D. or Masters degree in Biostatistics, Statistics, or a related field. </li> <li> Minimum 5 years relevant clinical biostatistics experience, preferably in oncology, diagnostics, or related biotech/pharma fields. </li> <li> Minimum 4 years practical experience with statistical analysis software such as R (preferred) or SAS. </li> </ul> KNOWLEDGE, SKILLS, AND ABILITIES: <ul> <li> Expert knowledge of probability theory and statistics including the ability to produce novel methods based on first principles understanding </li> <li> Solid foundation in clinical trial design approaches, regulatory expectations, and industry-aligned best practices </li> <li> Experience with complex clinical study designs, sample size determination, and advanced analytical methods, including non-inferiority and adaptive trial designs </li> <li> Familiarity with incorporating biomarker endpoints into trial design </li> <li> Demonstrated proficiency and enthusiasm for working in fast-paced, cross-functional environments with collaborators from diverse technical backgrounds </li> <li> Proven ability to independently develop high-quality, audience-tailored documentation that clearly communicates complex scientific and statistical concepts </li> </ul><div><div><div>The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years &amp; depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.</div><div>Remote USA</div><div>$134,400—$168,000 USD</div></div></div><div>OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit <a href="http://www.natera.com/">www.natera.com</a>. Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents.  Link: <a href="https://www.natera.com/notice-of-data-collection-california-residents" target="_blank">https://www.natera.com/notice-of-data-collection-california-residents/</a> Please be advised that Natera will reach out to candidates with a @<a href="http://natera.com/" target="_blank">natera.com</a> email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes. For more information: - <a href="https://www.bbb.org/article/tips/12261-bbb-tip-employment-scams" target="_blank">BBB announcement on job scams</a>  - <a href="https://www.fbi.gov/investigate/cyber" target="_blank">FBI Cyber Crime resource page</a> </div>