GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit <a href="https://www.genedx.com">www.genedx.com</a>. Summary  We are seeking a highly experienced and visionary Principal Software Architect to lead the design and development of our software architecture. The ideal candidate will have a deep understanding of software engineering principles, a proven track record of designing scalable and robust systems, and the ability to guide and mentor a team of engineers. This role is critical in ensuring an efficient streamlined workflow for our genetics testing platform. Job Responsibilities <ol> <li>Architectural Leadership:</li> <ul> <li>Work with key stakeholders across the company to define and drive the overall architecture strategy, ensuring alignment with business goals and technology standards.</li> <li>Lead the design and ensure the correct implementation of scalable, high-performance, and secure software systems tailored for genetic testing.</li> <li>Evaluate and recommend tools, technologies, and processes to ensure the highest quality product platform.</li> </ul> <li>Workflow Design and Automation:</li> <ul> <li>Design and implement efficient workflow orchestration solutions to streamline production processes.</li> <li>Ensure seamless integration of various software components and systems.</li> <li>Optimize workflows for performance, reliability, and scalability.</li> </ul> <li>Data Modeling:</li> <ul> <li>Design and implement comprehensive data models to support.</li> <li>Ensure data models are optimized for performance, scalability, and maintainability.</li> <li>Collaborate with data scientists and bioinformaticians to ensure accurate and reliable data representation.</li> </ul> <li>Best Practices:</li> <ul> <li>Establish and promote best practices in software development, deployment, and operations.</li> <li>Conduct code reviews and ensure adherence to coding standards and best practices.</li> <li>Foster a culture of continuous improvement and innovation within the engineering team.</li> </ul> <li>Technical Leadership:</li> <ul> <li>Provide technical guidance and mentorship to engineering teams.</li> <li>Stay current with emerging technologies and industry trends to drive innovation in genetics testing.</li> <li>Communicate complex technical concepts to non-technical stakeholders effectively.</li> </ul> </ol>  People Manager <ul> <li>No</li> </ul>  Education, Experience, and Skills <ul> <li>Education:</li> <ul> <li>Bachelor’s or Master’s degree in Computer Science, Engineering, or a related field.</li> </ul> <li>Experience:</li> <ul> <li>10+ years of experience in software development, with at least 5 years in an architectural role.</li> <li>Proven experience in designing and implementing large-scale, distributed systems.</li> <li>Strong background in multiple programming languages (e.g., Python, Java, .Net) and frameworks.</li> </ul> <li>Skills:</li> <ul> <li>Deep understanding of software architecture patterns (e.g., microservices, event-driven architecture).</li> <li>Expertise in cloud platforms (e.g., OCI, AWS, Azure).</li> <li>Strong problem-solving skills and the ability to think strategically.</li> <li>Excellent communication and leadership skills.</li> </ul> </ul> Preferred Qualifications: <ul> <li>Experience with DevOps practices and tools.</li> <li>Knowledge of data architecture and database design.</li> <li>Familiarity with machine learning and AI technologies.</li> <li>Experience in the healthcare or genetics testing industry.</li> </ul> Certificates, Licenses, Registrations <ul> <li>None</li> </ul> Physical Demands <ul> <li>This role requires extended periods of sitting while using a computer, involving frequent keyboarding and mouse usage. </li> </ul> Work Environment <ul> <li>This position is performed in a home office setting. Employees are expected to create a quiet, organized workspace conducive to productivity. The role may involve virtual collaboration with team members through video conferencing and digital communication tools. Employees should ensure reliable internet connectivity and have access to necessary technology to perform their job effectively. Flexibility in work hours may be required to accommodate team meetings and project deadlines. </li> </ul> #LI-REMOTE<div><div><div>Pay Transparency, Budgeted Range</div><div>$220,396—$275,495 USD</div></div></div><div>~ Science - Minded, Patient - Focused.  At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care. Experts in what matters most.  With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust. SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES. From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way: TECHNICAL EXPERTISE <ul> <li>High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.</li> <li>Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.</li> </ul> CLINICAL EXPERTISE <ul> <li>Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.</li> <li>Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.</li> <li>Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.</li> </ul> Learn more About Us <a href="https://www.genedx.com/about-us" target="_blank">here</a>. Our Culture At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, youre not just taking on a job—youre joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:   <ul> <li>Be bold in our vision &amp; brave in our execution. </li> <li>Communicate directly, with empathy. </li> <li>Do what we say were going to do.  </li> <li>Be adaptable to change.  </li> <li>Operate with a bias for action.    </li> </ul> Benefits include: <ul> <li>Paid Time Off (PTO)</li> <li>Health, Dental, Vision and Life insurance</li> <li>401k Retirement Savings Plan</li> <li>Employee Discounts</li> <li>Voluntary benefits</li> </ul> GeneDx is an Equal Opportunity Employer. All privacy policy information can be found <a href="https://www.genedx.com/privacy" target="_blank">here</a>.</div>

GeneDx

Principal Platform Engineer

GeneDx

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