Do you have deep Oncology expertise in clinical drug development and passion for leading late phase clinical program strategies? In this role, you can apply your skills to impact the way cancer is treated, and make a meaningful difference to patients!About AstraZeneca At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society.Oncology Research &amp; Development, Late Development Oncology At AstraZeneca, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. For us to be most effective, our Late Oncology team has four key disease areas; Lung Cancer, Breast Cancer, GU/GYN Cancer, and GI Cancer. The Late Development Oncology team is comprised of almost 2000 team members across clinical development and clinical operations. We have 16 assets in late development. We currently have over 120 Phase 3 and Lifecycle Management Oncology projects in our robust pipeline.What you’ll do:The Global Clinical Head has the chance to define a difference in people’s lives every day.In this position define and develop the clinical development plans for a product and ensures scientific value creation across lifecycle including initial approval, launch, lifecycle indications through to patent expiry. This role is externally facing leadership role.<ul><li>Delivery of the product Target Product Profile (TPP) and Target Product Claims (TPC) and maintenance of the Integrated Product Development Plan (iPDP).</li><li>Manage and develop a team of Global Development Medical Directors and Scientist Directors within a Global Product Team (GPT). Ensure delivery as a core member of the GPT team by providing overall clinical leadership of the asset.</li><li>Full responsibility for the planning, implementation and operation of the products drug development projects, including responsibility to:</li><li>Prepare clinical development plans that integrate pre-clinical and early clinical findings while working to ensure cross-functional alignment.</li><li>Design scientifically meticulous and cost-effective clinical protocols that are aligned with the clinical development plan.</li><li>Present and defend protocols and clinical development plans at internal governance forums.</li><li>Monitor study progress, ensure proper study conduct and adherence to the protocol, lead data review, evaluation, and analyses with support from Data Management and Stats &amp; Programming team.</li><li>Present study updates, interim results, and final headline data to senior management as required.</li><li>Lead preparation of documents for Regulatory and other agencies, such as Dossiers, NDA, BLAs, INDs, Safety and Annual reports, about complex clinical development issues (e.g., safety or efficacy).</li><li>Identify and assess clinical opportunities for the asset.</li><li>Work with functional management to develop plans and resolve issues.</li><li>Deliver product information to support internal and external business portfolio reporting (eg. CEO briefings, annual results communications etc).</li><li>Develop all external information on the product (including publications, regulatory documents, clinical trial registers etc).</li><li>Manage and protect the Intellectual Property (IP) assets of the product in consultation with IP and legal specialists including leadership of the Patent, Regulatory and Legal Defense Team.</li></ul>Essential for the role<ul><li>Qualified Physician (M.D. degree or international equivalent)</li><li>Oncology clinical drug development experience in academic institution or biopharma industry (Minimum 7 years of experience)</li><li>Deep oncology expertise. Fully conversant with science as it relates to the brand</li><li>Understands unmet market needs, creates a clear path forward, shows how to win</li><li>Robust knowledge of and evidence of successful oncology product development based on strong science, commercial insights, market research and competitive intelligence</li><li>Demonstrated understanding of oncology patient selection and stratification including companion/complementary diagnostic development and registration</li><li>Ability to provide clinical leadership for an asset to multiple stakeholders through clear communication and strategic thinking</li></ul>Desirable for the role<ul><li>Industry experience preferred</li><li>Medical specialty and sub-specialty training and certification in Oncology preferred</li><li>Clinical experience in treating and managing Cancer patients preferred</li><li>Credible with Key External Oncology Stakeholders, Payers and oncology scientific communities</li></ul>Why AstraZenecaWith our ground-breaking pipeline, the outlook is bright. Be proud to be part of a place that has achieved so much, yet is still moving forward. There’s no better time to join our global, growing enterprise as we lead the way for healthcare and society.The annual base pay (or hourly rate of compensation) for this position ranges from $323,216.00 - $484,824.00 . Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.  ​Date Posted11-Sep-2025Closing Date18-Sep-2025Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.