<h2>Career Category</h2>Information Systems<h2></h2><h2>Job Description</h2>Join Amgen’s Mission of Serving PatientsAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Principal Agentic AI Chatbot EngineerWhat you will doLet’s do this. Let’s change the world. In this vital role you will lead the design, development, and deployment of enterprise-scale agents and conversational bots. You will own the end-to-end architecture—from orchestration and retrieval to safety, observability, and CI/CD—so our agents reliably solve real business problems across R&amp;D, Manufacturing, and Commercial. As a senior IC “player-coach,” you’ll set technical standards, mentor teams, and partner with Security, Compliance, DevOps, and Product to ship secure, resilient, and cost-efficient solutions with measurable impact.Roles &amp; Responsibilities:<ul><li>Own the enterprise agent/bot platform architecture (cloud/on-prem), API contracts, and guardrails for multi-tenant use.</li><li>Design and ship production agentic systems: multi-agent planning, tool/function calling, workflow orchestration, and structured outputs.</li><li>Build high-containment bots for web/mobile/Slack/Teams/IVR with streaming responses and sub-second turn latency where required.</li><li>Implement retrieval &amp; memory (RAG, vector stores, knowledge graphs, session memory) with data contracts, lineage, and lifecycle governance.</li><li>Establish bot CI/CD: prompt &amp; config versioning, replay/conversation tests, feature flags, and automated rollbacks. Implement progressive delivery (blue-green, canary) with health checks, feature flags, and one-click rollback.</li><li>Stand up observability: tracing, metrics, and conversation analytics (containment, escalation, hallucination, CSAT, latency, cost per turn) with alerts and runbooks.</li><li>Integrate securely with enterprise systems (e.g., SAP, Salesforce, ServiceNow, MES/LIMS/ELN/QMS) via robust connectors and least-privilege tool access.</li><li>Embed safety, privacy, and compliance (content filtering, red-teaming, audit trails, secrets mgmt) aligned to GxP/21 CFR Part 11 and HIPAA/PII needs.</li><li>Optimize inference and cost (routing, caching, batching, distillation/quantization) and drive GPU/accelerator/FinOps strategy.</li><li>Evaluate and document trade-offs for models (open vs. proprietary), hosting options, and agent frameworks (e.g., LangChain, Semantic Kernel, Assistants APIs).</li><li>Translate domain needs (R&amp;D, Manufacturing, Commercial) into prioritized roadmaps; mentor teams and communicate technical trade-offs to stakeholders.</li></ul>What we expect of youWe are all different, yet we all use our unique contributions to serve patients. The professional we seek will have these qualifications.Basic Qualifications:Doctorate degree and 2 years of Computer Science, IT or related field experienceOrMaster’s degree and 4 years of Computer Science, IT or related field experienceOrBachelor’s degree and 6 years of Computer Science, IT or related field experienceOrAssociate’s degree and 10 years of Computer Science, IT or related field experienceOrHigh school diploma / GED and 12 years of Computer Science, IT or related field experiencePreferred Qualifications:<ul><li>3-5 years in AI/ML and enterprise software.</li><li>Knowledge graphs or structured reasoning (SPARQL, RDF/OWL) and tool-use planning with constraints.</li><li>Safety tooling (jailbreak detection, content moderation, PII redaction) and automated red-team pipelines.</li><li>Experience with privacy-preserving patterns (data masking, synthetic data, federated or on-prem inference).</li><li>Domain familiarity in biopharma workflows (clinical operations, quality, manufacturing/supply chain, field/commercial).</li><li>FinOps at scale: GPU fleet planning, utilization dashboards, commitment management.</li><li>Contributions to open source in LLM/agent ecosystems; patents or publications in conversational AI.</li><li>Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives.</li></ul>Good-to-Have Skills:<ul><li>Experience in Biotechnology or pharma industry is a big plus</li><li>Published thought-leadership or conference talks on enterprise GenAI adoption.</li><li>Master’s degree in Computer Science and or Data Science</li><li>Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery.</li><li>Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) are a plus.</li></ul>Soft Skills:<ul><li>Excellent analytical and troubleshooting skills.</li><li>Strong verbal and written communication skills</li><li>Ability to work effectively with global, virtual teams</li><li>High degree of initiative and self-motivation.</li><li>Ability to manage multiple priorities successfully.</li><li>Team-oriented, with a focus on achieving team goals.</li><li>Ability to learn quickly, be organized and detail oriented.</li><li>Strong presentation and public speaking skills.</li></ul>What you can expect of usAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:<ul><li>A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts</li><li>A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan</li><li>Stock-based long-term incentives</li><li>Award-winning time-off plans</li><li>Flexible work models, including remote and hybrid work arrangements, where possible</li></ul>Apply now and make a lasting impact with the Amgen team.careers.amgen.comIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.Application deadlineAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation..Salary Range189,750.00 USD - 233,440.00 USD